Lifetime relapse and its associated factors among people with schizophrenia spectrum disorders who are on follow up at Comprehensive Specialized Hospitals in Amhara region, Ethiopia: a cross-sectional study

Table 4 Description of Bivariable and Multivariable binary logistic regression analysis showing association between lifetime relapse and associated factors among participants with schizophrenia spectrum disorders in Comprehensive Specialized Hospitals, Amhara, 2020 (404)

Explanatory variables	Relapse		COR	AOR	P-value
Explanatory variables	Yes	No	COR	AOR	P-value
Sex
Male	136	89	1.32 (0.88, 1.96)	1.23 (0.790, 1.92)
Female	96	83
Marital status
Has spouse	45	23
No spouse	187	149	0.64 (0.37, 1.108)	0.69 (0.38, 1.27)
Income
< 2044	110	93	0.76 (0.51, 1.13)	0.68 (0.43, 1.07)
≥ 2044	122	79
Duration on treatment
Within 5 years	184	118	1.75 (1.11, 2.75)	1.71 (1.05, 2.81)	0.03
> 5 years	48	54
Comorbid mental illness
Yes	65	27	2.09 (1.26, 3.44)	1.84 (1.06, 3.18)	0.02
No	167	145
Medication adherence
Adherent	153	148
Non adherent	79	24	3.18 (1.91, 5.30)	2.23 (1.22, 4.07)	0.009
Medication side effect
Mild side effect	113	124	1
Moderate side effect	94	39	2.64 (1.68, 4.15)	1.52 (0.9, 2.57)
Severe side effect	25	9	3.04 (1.36, 6.80)	1.38 (0.52, 3.63)
Stressful events
Absent	24	29	1
1 or 2	53	81	0.79 (0.41, 1.50)	0.84 (0.43, 1.66)
≥ 3	155	62	3.02 (1.63, 5.59)	2.42 (1.2, 4.66)	0.008

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