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Promotion
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Promotion-prevention continuum
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Address entire community
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Nutrition and health care
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Integrated and multidisciplinary actions
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Housing and homelessness
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Healthcare-community collaborations
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Child abuse
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Negative consequences of parents’ divorce
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Family support
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Education and school-related problematic behavior
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Addictive substance use/dependence
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Personal skill development/management of stressful life events
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Primary prevention
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Life-span continuum (Early stage-intensification of risk continuum)
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Universal
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Brain development and anti-inflammatory neuroprotection (Phosphatidylcholine and N-acetylcysteine supplementation)
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Pathophysiological mechanisms during early development
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Neuroinflammation, oxidative stress, and microbiota dysbiosis (Omega-3 fatty acid, vitamin, sulforaphane, and prebiotic supplementation)
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Bullying and peer rejection (School-based behavioral interventions)
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Substance abuse
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Brain plasticity, structure, connectivity, and cognitive functioning (Lifetime exercise training)
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Selective
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Parental mental illness
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Poor validity of boundaries between diagnostic categories
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Paternal age
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Lack of evidence-based selective interventions
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Maternal and obstetric complications of pregnancy
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Youth with family history of severe mental illness (genetic risk)
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Season of birth
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Ethnic minority
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Immigration status
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Urban environment
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Infections
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Childhood adversities, socio-financial disadvantage, maladaptive behavior (Nursing home visits, school-based interventions, home teaching)
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Vitamin D deficiency and malnutrition
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Low premorbid intelligence quotient
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Traumatic brain injury
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Heavy tobacco and cannabis use
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Indicated
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Psychosis-risk state
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Limited psychosis detection rate
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Service engagement and liaison with secondary intervention services
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Pluripotent and trans-diagnostic risk state
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Duration of untreated illness
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Multi-component symptom intervention
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Control of symptoms and self-control of emotion and behavior (Cognitive behavioral, relaxation, mindfulness, and meditation strategies)
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Poor social problem solving and low quality of social support (Social skill training)
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Interpersonal conflict (Interpersonal psychotherapy, forgiveness programs)
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Loneliness and social difficulties in general (Resilience training)
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Secondary prevention
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Collaborative care
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Primary care-specialist mental health care collaborations
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Recovery
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Duration of untreated illness
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Poor treatment response/treatment resistance
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Poor psycho-social well-being and functioning
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Comorbid substance use
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Burden on families
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Tertiary prevention
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Recovery
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Disease progression
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Poor treatment response/treatment resistance
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Interventions to prevent multiple relapses
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Poor psycho-social well-being and functioning
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Comorbid substance use
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Burden on families
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