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Table 4 Summary results from post hoc mixed-model analysis of primary and secondary outcomes, with baseline measurement (i.e. age, gender, HADS) included as covariate

From: Effect of adding a psychological intervention to routine care of common mental disorders in a specialized mental healthcare facility in Pakistan: a randomized controlled trial

Primary and secondary outcomes

Visit

Difference in least squares mean for intervention vs treatment as usual (95% CI)

P value

HADS Anxiety

Pre-treatment

  

Post-treatment

− 2.67 (− 4.32 to − 1.03)

0.002

Follow-up

− 1.84 (− 3.56 to − 0.13)

0.04

HADS Depression

Pre-treatment

  

Post-treatment

− 1.98 (− 3.41 to − 0.55)

0.007

Follow-up

− 1.43 (− 2.92 to 0.07)

0.06

HADS

Pre-treatment

  

Post-treatment

− 4.65 (− 7.27 to − 2.03)

0.0006

Follow-up

− 3.20 (− 5.92 to − 0.48)

0.02

WHO DAS

Pre-treatment

  

Post-treatment

− 3.81 (− 6.59 to − 1.04)

0.008

Follow-up

− 4.44 (− 7.34 to − 1.55)

0.003

PCL

Pre-treatment

  

Post-treatment

− 3.30 (− 8.71 to 2.12)

0.23

Follow-up

− 5.17 (− 11.08 to − 0.33)

0.04

PHQ

Pre-treatment

  

Post-treatment

− 2.51 (− 4.96 to − 0.06)

0.04

Follow-up

− 3.04 (− 5.32 to − 0.76)

0.01

Days of these difficulties present

Pre-treatment

  

Post-treatment

− 4.33 (− 7.90 to − 0.77)

0.02

Follow-up

− 2.84 (− 6.47 to 0.79)

0.12

Days of total disability

Pre-treatment

  

Post-treatment

− 2.51 (− 5.18 to 0.15)

0.06

Follow-up

− 1.69 (− 4.41 to 1.02)

0.22

Days of activity reduce

Pre-treatment

  

Post-treatment

− 3.15 (− 6.41 to 0.10)

0.06

Follow-up

− 1.95 (− 5.27 to 1.37)

0.25

Perceived social support

Pre-treatment

  

Post-treatment

4.45 (− 1.05 to 9.95)

0.11

Follow-up

2.52 (− 3.22 to 8.27)

0.39

PSYCHLOPS

Pre-treatment

  

Post-treatment

− 2.58 (− 4.39 to − 0.77)

0.006

Follow-up

− 1.66 (− 3.54 to 0.23)

0.08

  1. HADS Hospital Anxiety and Depression Scale, WHODAS WHO Disability Assessment Schedule 2.0, PCL Post-traumatic stress disorder checklist, PHQ Patient Health Questionnaire, PSYCHLOPS Psychological Outcome Profile
  2. Post-treatment = 7-week after baseline; Follow-up = 20 weeks after baseline