Table 5 Primary analysis of depression and disability outcomes in the intervention and control groups at 1 month and 2 months (Period 1)
Period 1 | Unadjusted mean | Adjusted difference (primary analysis) | p value | Adjusted difference (robustness checking) | p-value | ||
|---|---|---|---|---|---|---|---|
Immediate intervention (n0 = 190) | Delayed intervention (n0 = 185) | ||||||
Primary outcome | |||||||
SRQ-20 > 7 (%) | Baseline | 100% (190/190) | 100% (185/185) | – | – | – | – |
1 month | 57.1% (89/156) | 71.2% (99/139) | OR = 0.47 95% CI (0.28, 0.78) | 0.0038 | OR = 0.39 95% CI (0.23, 0.64) | 0.0002 | |
2 month | 26.4% (42/159) | 42.3% (58/137) | OR = 0.42 95% CI (0.28, 0.63) | < 0.0001 | OR = 0.33 95% CI (0.21, 0.52) | < 0.0001 | |
Secondary outcomes | |||||||
SRQ-20 | Baseline | 11.0 (2.5) | 10.7 (2.2) | – | – | – | – |
1 month | 8.4 (4.7) | 9.9 (4.3) | Δ = − 1.76 95% CI (− 2.72, − 0.79) | 0.0004 | Δ = − 1.84 95% CI (− 2.81, − 0.86) | 0.0002 | |
2 month | 5.2 (4.6) | 7.5 (4.5) | Δ− 2.42 95% CI (− 3.38, − 1.40) | < 0.0001 | Δ = − 2.50 95% CI (− 3.47, − 1.51) | < 0.0001 | |
WHODAS2.0 | Baseline | 26.9 (7.6) | 26.7 (8.9) | – | – | – | – |
1 month | 22.9 (9.6) | 24.5 (9.3) | Δ = − 1.86 95% CI (− 3.82, 0.06) | 0.059 | Δ = − 1.93 95% CI = (− 3.85, -0.02) | 0.047 | |
2 month | 18.3 (7.4) | 21.0 (8.3) | Δ = − 2.63 95% CI (− 4.32, − 0.99) | 0.002 | Δ = − 2.68 95% CI = (− 4.34, − 1.02) | 0.0016 | |