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Table 5 Change in symptom severity and impairment score for depression, epilepsy and psychosis patients at PRIME implementation clinics in Kamuli District, Uganda, 2015–2017

From: Evaluation of the impacts of a district-level mental health care plan on contact coverage, detection and individual outcomes in rural Uganda: a mixed methods approach

Disorder

Measurement

Baseline score

Midlinea score

Endline score

Midlinea difference in score vs. baseline (95% CI)

Endline difference in score vs. baseline (95% CI)

Outcome

Depression

 Symptom severity

Mean PHQ-9 (SD)

16.3 (4.6)

8.4* (6.3)

6.4* (5.6)

− 7.9 (− 12.6, − 3.2)

− 9.9 (− 14.4, − 5.4)

 Impairment

Mean WHODAS (SD)

48.4 (18.0)

26.7* (22.1)

22.6* (22.3)

− 21.7 (− 35.4, − 7.9)

− 25.8 (− 39.2, − 12.4)

Psychosis

 Impairment

Mean WHODAS (SD)

34.9 (27.2)

14.2* (18.8)

15.7* (20.9)

− 20.7 (− 31.3, − 10.1)

− 19.2 (− 30.1, − 8.4)

Epilepsy

 Symptom severity

Median # seizures in past 30 days (IQR)

3 (1–5)

1** (0–4)

2** (0–4)

  

 Impairment

Mean WHODAS (SD)

35.9 (23.6)

26.9* (29.0)

23.5* (27.9)

− 9.1 (− 17.4, − 0.8)

− 12.4 (− 20.5, − 4.4)

  1. * Negative binomial regression P < 0.05 for difference of score vs. baseline
  2. ** Wilcoxon Sign-rank P < 0.05 for difference of score vs. baseline
  3. a3 months for depression, 6 months for psychosis and epilepsy