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Table 5 Change in symptom severity and impairment score for depression, epilepsy and psychosis patients at PRIME implementation clinics in Kamuli District, Uganda, 2015–2017

From: Evaluation of the impacts of a district-level mental health care plan on contact coverage, detection and individual outcomes in rural Uganda: a mixed methods approach

Disorder Measurement Baseline score Midlinea score Endline score Midlinea difference in score vs. baseline (95% CI) Endline difference in score vs. baseline (95% CI)
Outcome
Depression
 Symptom severity Mean PHQ-9 (SD) 16.3 (4.6) 8.4* (6.3) 6.4* (5.6) − 7.9 (− 12.6, − 3.2) − 9.9 (− 14.4, − 5.4)
 Impairment Mean WHODAS (SD) 48.4 (18.0) 26.7* (22.1) 22.6* (22.3) − 21.7 (− 35.4, − 7.9) − 25.8 (− 39.2, − 12.4)
Psychosis
 Impairment Mean WHODAS (SD) 34.9 (27.2) 14.2* (18.8) 15.7* (20.9) − 20.7 (− 31.3, − 10.1) − 19.2 (− 30.1, − 8.4)
Epilepsy
 Symptom severity Median # seizures in past 30 days (IQR) 3 (1–5) 1** (0–4) 2** (0–4)   
 Impairment Mean WHODAS (SD) 35.9 (23.6) 26.9* (29.0) 23.5* (27.9) − 9.1 (− 17.4, − 0.8) − 12.4 (− 20.5, − 4.4)
  1. * Negative binomial regression P < 0.05 for difference of score vs. baseline
  2. ** Wilcoxon Sign-rank P < 0.05 for difference of score vs. baseline
  3. a3 months for depression, 6 months for psychosis and epilepsy