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Table 3 The Hazard Ratio for relapse by characteristics of patients with first-episode schizophrenia

From: Risk factors for relapse in patients with first-episode schizophrenia: Analysis of the Health Insurance Review and Assessment Service data from 2011 to 2015

Characteristics Categories Status Univariate Multivariate
No relapse Relapse Hazard ratio 95% CI Hazard ratio 95% CI
Gender Male 1654 635 1.00 (0.90–1.12) 0.95 (0.85–1.06)
Female 1648 630 1.00 (reference)
Age (years) 3302 1265 0.98* (0.97–0.99) 0.96* (0.95–0.98)
Geographic location Metropolitan City 1727 632 1.00 (reference)
Province 1575 633 1.09 (0.98–1.22) 1.02 (0.92–1.14)
Medical benefits Non-recipient 3057 1187 1.00 (reference)
Recipient 245 78 0.85 (0.68–1.07) 0.85 (0.68–1.07)
Type of medical institution Tertiary hospital 543 230 1.00 (reference)
Community hospital 846 440 1.26* (1.10–1.43) 1.17* (1.02–1.33)
Clinic 1321 358 0.73* (0.63–0.83) 0.75* (0.63–0.90)
Antipsychotic drugs Monotherapy 1585 448 1.00 (reference)
Combination therapy 1442 602 1.40* (1.24–1.58) 1.04 (0.88–1.21)
Other drugs 275 215 2.29* (1.95–2.70) 2.09* (1.77–2.46)
Medication adherence 0–50% 1176 660 1.60* (1.42–1.80) 1.59* (1.41–1.80)
50–80% 452 122 0.88 (0.72–1.07) 0.94 (0.77–1.15)
More than 80% 1674 483 1.00 (reference)
Treatment after initial diagnosis Outpatient treatment 2352 759 1.00 (reference)
Inpatient treatment 950 506 1.50* (1.34–1.67) 1.46* (1.24–1.71)
  1. Multivariate hazard ratio was calculated including all variables in the table
  2. CI confidence interval
  3. * P < 0.05