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Table 3 The Hazard Ratio for relapse by characteristics of patients with first-episode schizophrenia

From: Risk factors for relapse in patients with first-episode schizophrenia: Analysis of the Health Insurance Review and Assessment Service data from 2011 to 2015

Characteristics

Categories

Status

Univariate

Multivariate

No relapse

Relapse

Hazard ratio

95% CI

Hazard ratio

95% CI

Gender

Male

1654

635

1.00

(0.90–1.12)

0.95

(0.85–1.06)

Female

1648

630

1.00 (reference)

Age (years)

3302

1265

0.98*

(0.97–0.99)

0.96*

(0.95–0.98)

Geographic location

Metropolitan City

1727

632

1.00 (reference)

Province

1575

633

1.09

(0.98–1.22)

1.02

(0.92–1.14)

Medical benefits

Non-recipient

3057

1187

1.00 (reference)

Recipient

245

78

0.85

(0.68–1.07)

0.85

(0.68–1.07)

Type of medical institution

Tertiary hospital

543

230

1.00 (reference)

Community hospital

846

440

1.26*

(1.10–1.43)

1.17*

(1.02–1.33)

Clinic

1321

358

0.73*

(0.63–0.83)

0.75*

(0.63–0.90)

Antipsychotic drugs

Monotherapy

1585

448

1.00 (reference)

Combination therapy

1442

602

1.40*

(1.24–1.58)

1.04

(0.88–1.21)

Other drugs

275

215

2.29*

(1.95–2.70)

2.09*

(1.77–2.46)

Medication adherence

0–50%

1176

660

1.60*

(1.42–1.80)

1.59*

(1.41–1.80)

50–80%

452

122

0.88

(0.72–1.07)

0.94

(0.77–1.15)

More than 80%

1674

483

1.00 (reference)

Treatment after initial diagnosis

Outpatient treatment

2352

759

1.00 (reference)

Inpatient treatment

950

506

1.50*

(1.34–1.67)

1.46*

(1.24–1.71)

  1. Multivariate hazard ratio was calculated including all variables in the table
  2. CI confidence interval
  3. * P < 0.05