Evaluation of outcomes for psychosis and epilepsy treatment delivered by primary health care workers in Nepal: a cohort study

Table 4 Clinical outcome summary scores from clinician interview for patients with epilepsy

Seizures	Program (n = 83)			Control (n = 22)			Study arm comparison		Full cohort (n = 105)
Seizures	n	%	95% CI	n	%	95% CI	RR (95% CI)	P-value*	n	%	95% CI	RR (95% CI)	P-value**
Recent							0.52 (0.29–0.95)	0.03				0.33 (0.24–0.45)	< 0.0001
Baseline	68	82	(72–90)	20	91	(71–99)			88	84	(75–90)
end point	19	23	(14–33)	10	45	(24–68)			29	28	(19–37)

HAM-D	Mean	SD	Mean	SD	Effect size F, partial eta²	P-value***	Mean	SD	Effect size Z, r	P-value****
Baseline	10.9	6.2	10.0	6.4	1.62, 0.02	0.21	10.7	6.2	7.43, 0.73	> 0.0001
end point	4.5	3.3	5.6	5.7			4.8	3.9
Δ score	− 6.4	6.2	− 4.4	6.2			− 5.9	6.3

HAM-D Hamilton Depression Scale, CI confidence interval
* Wald test statistic p-value from logistic regression model comparing Program to Control outcomes, adjusted for seizure at baseline
** McNemar’s Exact χ² test for binomial paired data: comparing baseline to end point proportion of clinical outcome (i.e., recent attack) for the full cohort
*** P-value taken from ANCOVA (analysis of covariance) for each scale comparing program vs. control scores at end point, adjusted for baseline score
**** P-value from Wilcoxon Signed-Rank Test comparing baseline to end point scores (full cohort)

ISSN: 1752-4458