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Table 4 Clinical outcome summary scores from clinician interview for patients with epilepsy

From: Evaluation of outcomes for psychosis and epilepsy treatment delivered by primary health care workers in Nepal: a cohort study

Seizures Program (n = 83) Control (n = 22) Study arm comparison Full cohort (n = 105)
n % 95% CI n % 95% CI RR (95% CI) P-value* n % 95% CI RR (95% CI) P-value**
Recent 0.52 (0.29–0.95) 0.03     0.33 (0.24–0.45) < 0.0001
Baseline 68 82 (72–90) 20 91 (71–99)    88 84 (75–90)   
end point 19 23 (14–33) 10 45 (24–68)    29 28 (19–37)   
HAM-D Mean SD   Mean SD Effect size
F, partial eta2
P-value***   Mean SD Effect size
Z, r
P-value****
Baseline 10.9 6.2   10.0 6.4 1.62, 0.02 0.21   10.7 6.2 7.43, 0.73 > 0.0001
end point 4.5 3.3   5.6 5.7     4.8 3.9   
Δ score − 6.4 6.2   − 4.4 6.2     − 5.9 6.3   
  1. HAM-D Hamilton Depression Scale, CI confidence interval
  2. * Wald test statistic p-value from logistic regression model comparing Program to Control outcomes, adjusted for seizure at baseline
  3. ** McNemar’s Exact χ2 test for binomial paired data: comparing baseline to end point proportion of clinical outcome (i.e., recent attack) for the full cohort
  4. *** P-value taken from ANCOVA (analysis of covariance) for each scale comparing program vs. control scores at end point, adjusted for baseline score
  5. **** P-value from Wilcoxon Signed-Rank Test comparing baseline to end point scores (full cohort)