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Table 3 Qualitative summary of the efficacy of interventions by type of mental health outcome

From: Common mental disorders in asylum seekers and refugees: umbrella review of prevalence and intervention studies

Outcomes

Interventions

Comparison

Study design

No of patients

Systematic reviews

RCTs

CCTs

Pre-post

PTSD/trauma-related symptoms

NET

Inactive (N = 8)

  

640

Crumlish and O’Rourke [21]; McFarlane and Kaplan [22]; Nickerson et al. [23]; Nosè et al. [20]; Palic and Elklit [24]; Patel et al. [25]; Robjant and Fazel [27]

Supportive counseling, stress inoculation training, trauma counselling (N = 3)

  

Without control group (N = 1)

  

KIDNET

Inactive (N = 1)

  

26

Crumlish and O’Rourke [21]; Robjant and Fazel [27]

EMDR

Stabilisation (no exposure) (N = 1)

  

20

Patel et al. [25]

CBT/culturally sensitivity CBT/CPT

Inactive (N = 8)

■■

 

455

Crumlish and O’Rourke [21]; McFarlane and Kaplan [22]; Nickerson et al. [23]; Nosè et al. [20]; Palic and Elklit [24]; Peltonen and Punamaki [26]; Sonne et al. [29]; Sullivan and Simonson [30]; Tyrer and Fazel [31]; Williams and Thompson [33]

Exposure therapy (N = 1)

  

Without control group (N = 3)

  

▲▲

Testimony therapy

Without control group (N = 1)

  

20

McFarlane and Kaplan [22]; Nickerson et al. [23]; Palic and Elklit [24]

Trauma-focused therapy

Inactive (N = 2)

 

■■

 

197

McFarlane and Kaplan [22]; Nickerson et al. [23]; Nosè et al. [20]; Palic and Elklit [24]; Sullivan and Simonson [30]; Tyrer and Fazel [31]

Child-centered play therapy (N = 1)

  

Without control group (N = 1)

  

Multimodal interventions/multidisciplinary treatments

Without control group (N = 7)

  

▲▲▲

248

McFarlane and Kaplan [22]; Nickerson et al. [23]; Palic and Elklit [24]; Peltonen and Punamaki [26]; Slobodin and de Jong [28]; Sullivan and Simonson [30]; Tyrer and Fazel [31]; Van Wyk and Schweitzer [32]

Antidepressantsa

Without control group (N = 1)

  

32

Crumlish and O’Rourke [21]; Sonne et al. [29]

Antidepressantsb + supportive therapy

Without control group (N = 2)

  

▲▲

68

Sonne et al. [29]

Psychotropic medication + psychodinamic therapy

Inactive (N = 1)

   

50

Palic and Elklit [24]; Sonne et al. [29]

Anxiety symptoms

NET

Inactive (N = 1)

  

43

Crumlish and O’Rourke [21]; Nickerson et al. [23]; Palic and Elklit [24]; Robjant and Fazel [27]

Supportive counseling (N = 1)

  

EMDR

Stabilisation (no exposure) (N = 1)

  

20

Patel et al. [25]

CBT/culturally sensitivity CBT/CPT

Inactive (N = 4)

  

189

Crumlish and O’Rourke [21]; McFarlane and Kaplan [22]; Nickerson et al. [23]; Palic and Elklit [24]; Peltonen and Punamaki [26]; Sonne et al. [29]; Sullivan and Simonson [30]; Tyrer and Fazel [31]

Exposure therapy (N = 1)

 

Without control group (N = 2)

  

Multimodal interventions/multidisciplinary treatments

Without control group (N = 6)

  

▲▲

218

McFarlane and Kaplan [22]; Nickerson et al. [23]; Palic and Elklit [24]; Peltonen and Punamaki [26]; Slobodin and de Jong [28]; Van Wyk and Schweitzer [32]; Tyrer and Fazel [31]

Depressive symptoms

NET

Inactive (N = 5)

 

250

Crumlish and O’Rourke [21]; McFarlane and Kaplan [22]; Nickerson et al. [23]; Nosè et al. [20]; Palic and Elklit [24]; Patel et al. [25]; Robjant and Fazel [27]

Supportive counseling, stress inoculation training (N = 2)

  

Without control group (N = 1)

  

EMDR

Stabilisation (no exposure) (N = 1)

  

20

Patel et al. [25]

CBT/culturally Sensitivity CBT/CPT

Inactive (N = 5)

  

389

Crumlish and O’Rourke [21]; McFarlane and Kaplan [22]; Nickerson et al. [23]; Nosè et al. [20]; Palic and Elklit [24]; Peltonen and Punamaki [26]; Sonne et al. [29]; Sullivan and Simonson [30]; Tyrer and Fazel [31]

Exposure therapy (N = 1)

  

Without control group (N = 3)

  

▲▲

Testimony therapy

Without control group (N = 1)

  

20

McFarlane and Kaplan [22]; Nickerson et al. [23]; Palik and Elklit [24]

Multimodal interventions/multidisciplinary treatments

Without control group (N = 7)

  

▲▲▲

248

McFarlane and Kaplan [22]; Nickerson et al. [23]; Palic and Elklit [24]; Peltonen and Punamaki [26]; Slobodin and de Jong [28]; Sullivan and Simonson [30]; Van Wyk and Schweitzer [32]; Tyrer and Fazel [31]

Antidepressantsc

Without control group (N = 1)

   

32

Crumlish and O’Rourke [21]; Sonne et al. [29]

  1. NET narrative exposure therapy, KIDNET narrative exposure therapy for children, EMDR eye movement desensitisation and reprocessing, CBT cognitive behavioral therapy, CPT cognitive processing therapy
  2. ■ = controlled clinical trial (CCT) showing a statistically significant positive effect, □ = controlled clinical trial (CCT) failing to show a statistically significant positive effect, = randomised clinical trial (RCT) showing a statistically significant positive effect, = randomised clinical trial (RCT) failing to show a statistically significant positive effect, ▲ = study without control group showing a statistically significant positive effect, = study without control group failing to show a statistically significant positive effect
  3. aParoxetine, sertraline and venlafaxine
  4. bTCA or MAOI, or a combination of these medications
  5. cOnly venlafaxine did not show improvement in Beck depression inventory