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Table 2 WHO three essential antipsychotics and other drugs on the 'Essential' list (by drug class) to which they have been compared within randomized trials

From: Using the needs of WHO to prioritise Cochrane reviews: The case of antipsychotic drugs

  RCTs Total number of people Cochrane review Reference Up to date?
Chlorpromazine
   vs anticonvulsant agents 2 118   
   vs antidepressants 12 732 [22, 23]
   vs antihypertensive agents 8 286   
   vs antiparkinsonian agents 3 80   
   vs antituberculosis agents 1 25   
   vs barbiturates 3 750   
   vs benzodiazepines 9 457 [24, 25]
   vs mood stabilizers 2 49 [2628]
   vs opioid agonist 1 340   
   vs opioid antagonist 1 60   
Fluphenazine decanoate
   vs antihypertensive agents 1 17   
   vs antituberculosis agents 1 55   
Haloperidol
   vs antiarrhythmic agents 2 30   
   vs antidepressants 10 774 [22, 23]
   vs antidopaminergic agents 4 146   
   vs antigout agents 1 46   
   vs antihypertensive agents 3 122   
   vs antineoplastic agents 3 101   
   vs antiparkinsonian agents 8 265   
   vs antiprogesterone agents 1 80 [29]
   vs benzodiazepines 35 4012 [24, 25]
   vs ethanol 1 35   
   vs glucose 1 unclear   
   vs mood stabilizers 23 1648 [2628]
   vs stimulant agents 1 20   
  1. RCTs: Randomized Controlled Trials
  2. Vs: Versus
  3. : Systematic Reviews or update already exist
  4. ✗: Systematic Reviews or update do not exist