Table 1 WHO three essential antipsychotics and possible comparisons
From: Using the needs of WHO to prioritise Cochrane reviews: The case of antipsychotic drugs
RCTs | Total number of people | Cochrane review | Reference | Up to date? | |
|---|---|---|---|---|---|
Chlorpromazine | |||||
   vs fluphenazine depot | 7 | 1314 | ✓ | [13] | ✗ |
   vs haloperidol | 51 | 6001 | ✓ | [14] | ✗ |
   vs placebo | 233 | 19854 | ✓ | [15] | ✗ |
   Withdrawal | 1 | 32 | ✓ | [16] | ✗ |
   Techniques of administration | 8 | 669 | ✗ | ||
   Dose | 15 | 1279 | ✓ | [17] | ✗ |
   In specific circumstances | 1 | 30 | ✓ | [18] | ✗ |
Fluphenazine Decanoate | |||||
   vs chlorpromazine | 7 | 1314 | ✓ | [13] | ✗ |
   vs haloperidol | 19 | 2339 | ✓ | [13] | ✗ |
   vs placebo | 4 | 456 | ✓ | [13] | ✗ |
   Withdrawal | 0 | 0 | ✗ | ||
   Techniques of administration | 0 | 0 | ✗ | ||
   Dose | 3 | 394 | ✗ | ||
   In specific circumstances | 0 | 0 | ✗ | ||
Haloperidol | |||||
   vs chlorpromazine | 51 | 6001 | ✓ | [14] | ✗ |
   vs fluphenazine depot | 19 | 2339 | ✓ | [13] | ✗ |
   vs placebo | 237 | 41321 | ✓ | [19] | ✗ |
   Withdrawal | 3 | 126 | ✗ | ||
   Techniques of administration | 50 | 10583 | ✗ | ||
   Dose | 126 | 16470 | ✓ | [20] | ✗ |
   In specific circumstances | 4 | 1117 | ✓ | [21] | ✗ |